At 9:45 a.m. at the Los Angeles Convention Center, the line to enter the South Hall stretches hundreds of feet. There are cosplayers demonstrating unbelievable loyalty to an assortment of video games, advertising industry experts comparing conference swag, and college-age true believers eager for a game development career. Everyone is waiting for the 10 a.m. opening of E3—a massive gaming conference with approximately 50,000 guests.

Image: http://www.fastcompany.com/

The year was 2012 B.T. (Before Tinder). I was building a mobile dating app called "Find Your Lobster ," which was, to our knowledge, the first mobile app that leveraged Facebook to help you date your friends’ single friends.

People were skeptical. In those years, the general consensus was that no "desirable" (the accepted, politically correct version of "good-looking") people under the age of 30 would ever dream of using a dating app—especially one that made them sign in with Facebook. Why would they? They were good-looking!

Image: Flickr user Biodiversity Heritage Library

I/O: The strategic supernova in cancer today With the big cancer confab ASCO 2016 fading into memory, R&D teams everywhere are getting back to work on their cancer programs – and across the industry many of them will be doing the same work, on the same targets, supporting the exploding supernova known as immuno-oncology.

Image: http://medcitynews.com

The White House’s Cancer Moonshot 2020 is about much more than clinical research. Data, IT and patient engagement are major components.

Vice President Joe Biden on Wednesday is hosting the first National Cancer Moonshot Summit on the campus of Howard University in Washington, and lots of news is being made.

Granted, there was the usual complement of cheerleading and optimism, as some observed.

Image: http://medcitynews.com

Vice President Joe Biden, who has personal experience of the heartbreak that cancer causes, has taken on humanity’s mortal enemy and aims to end the disease “as we know it.”

On Wednesday, at the National Cancer Moonshot Summit, Biden unveiled details of the battle lines and the strategies to outwit the disease. What’s more if Biden and other stakeholders are successful in this goal, another scourge of healthcare will also receive a death knell: silo, which over the years has become healthcare’s very own four-letter word.

The Leave campaign’s victory, with a margin of 3.8 percentage points, has likely ushered in a protracted phase of uncertainty for the UK, EU, and global economies. A systemic shock cutting across industries and borders, Brexit poses significant strategic challenges for business leaders as they navigate the fallout. Judging by our interactions with CEOs around the world to date, some of their burning questions are:

A bill that would phase out North Dakota’s angel fund investment tax credit and expand the seed capital investment tax credit was forwarded out of an interim committee Wednesday, setting the stage for further debate during next year’s regular session.

Members of the interim Political Subdivision Taxation Committee are expecting at their next meeting to also forward a competing bill that would beef up reporting requirements on the angel fund.

KANSAS CITY, Mo., June 29, 2016 /PRNewswire/ -- Angel investors – accredited individuals who collectively support the American startup industry with some $24 billion of capital per year – maintain diversified portfolios that represent roughly 5 percent of total held assets, with median investments of $25,000 per deal.  Today, the Angel Capital Association (ACA) and Wharton Entrepreneurship at the University of Pennsylvania released these and other early insights from the ongoing "The American Angel" survey, which is designed to provide the deepest research to date into the characteristics of angel investors.  The survey is open for more angels to participate.

Businesses that set out to change the world might want to start in D.C.

That’s according to a new study from D.C.-based S&R Foundation’s Halcyon Incubator, which calls Washington the best U.S. city for “social entrepreneurs” — startup founders that attempt to solve social problems with scalable businesses, like the Georgetown grads tackling food-waste with their juicing company, Misfit Juicery.

The Nova Scotia government is developing a private-sector venture capital fund to help the province’s businesses create jobs, grow and compete internationally.

“When businesses have better access to capital, it means more jobs for Nova Scotians,” said Business Minister Mark Furey.

“The creation of this fund will mean stronger communities and more opportunities for young people to live and work here in Nova Scotia.”

Less than a decade ago, our planet reached a key inflection point: For the first time in human history, the majority of the population resided in cities. In fact, over 50 percent of the world's population has now settled on less than two percent of the Earth's surface area.  

Rapid urban migration and an explosive growth in megacities are two international phenomena that are putting present-day metropolitan areas under enormous strain. Factor in global warming, resource scarcity, and a bourgeoning middle class, and it's clear that we need smart solutions to carry our cities forward into the future.

When considering the most exciting elements of entrepreneurial life, you probably don’t immediately think of the word “infrastructure.” Foundations, wiring, plumbing — surely, these aren’t the things that provide a startup with the innovative spark it needs to grow.

But infrastructure goes way beyond pipes and wires; it’s your startup’s internal road map. It’s your HR systems, sales processes, and marketing protocols. It embodies some of the most vital and creative parts of your operation, and it helps you achieve your biggest goals.

Mark Cuban, owner of the Dallas Mavericks and star of ABC’s Shark Tank, believes that kids should start learning about entrepreneurship from a young age. To get them excited about business, Cuban co-authored a book with Shaan Patel, the founder of test-prep company Prep Expert, and Ian McCue, the founder of Spark Skill, called How Any Kid Can Start a Business. The book will teach kids the fundamentals of entrepreneurship and hopes to inspire them to consider it as a career option.

You want to start a startup. Welcome to the club—me, too.

Many articles will tell you the things you need—education, money, grit—but what it comes down to is that you have to be the catalyst. It’s not going to come to you; you’ve got to go to it. That means you have to be proactive, methodical, and strategic. You need to come up with a personal five-year plan that outlines what you’re going to do and what steps you’ll take to get there. You’ll have to make sure that every step you’re taking today is directionally in line with that five-year plan. Here are some of the components you need to consider in building the right plan:

In its inaugural budget, the federal Liberal government vowed to develop a bold, new innovation agenda as the centrepiece of its strategy to bolster long-term economic growth. This was the right call, not only because it plays well—who would disagree with Canada becoming “a centre of global innovation?”—but also because innovation-driven productivity growth is unequivocally essential for our future prosperity.

Your vacation dollars should work as hard as you do.

No one likes to waste money, least of all on a vacation. Nothing kills the buzz of a dream trip faster than standing on line for that top tourist attraction, handing over your hard-earned cash, and discovering that it was all a bunch of hyped holiday hooey.

To save you money and time, we’ve compiled a list of 20 sights that are, in fact, worth every dollar.

Have you noticed that the really big startup wins in the last couple of decades have come from creating and dominating new market categories, more than just new solutions? Steve Jobs was a master new category king, by preaching the need for new thinking as he introduced the iPad, iPhone, and Apple Watch. Uber and Airbnb did the same for transportation and hospitality.

SACRAMENTO, Calif.--(BUSINESS WIRE)--California Life Sciences Association (CLSA), the statewide public policy organization representing over 750 of California’s leading life sciences innovators, today issued the following statement regarding Senate Bill (SB) 1010, which passed by the California Assembly Health Committee yesterday. SB 1010 prioritizes paperwork, red tape and bureaucracy over research, and instead of improving patient access and affordability, places patients in California at risk. This statement can be attributed to Sara Radcliffe, President & CEO, California Life Sciences Association (CLSA).

According to new findings in the Global Accelerator Report 2015 recently issued by Gust and Fundacity, in 2015 more than $191MM was invested into more than 8,800 startups across five major regions, including the United States and Canada, Latin America, Europe, the Middle East, and Asia and Oceania.

Image: http://www.forbes.com 

Companies chronically underestimate how much time and hard work is involved in running an equity crowdfunding campaign. It’s often only after they get some way down the track that they realise what is involved, and it’s natural to feel overwhelmed and look for help.

In response, equity crowdfunding consultants have arrived on the scene. They might be individuals who promise to lend their skill set from a variety of backgrounds such as finance, marketing or public relations. There are also large crowdfunding agencies which offer a suite of services, for just about everything a campaign could need.