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GlaxoSmithKline Plc (GSK), the U.K.’s largest drugmaker, will work with the U.S. government to develop antibiotics for resistant infections and bioterrorist threats in an agreement valued at as much as $200 million.

The company will collaborate with the Biomedical Advanced Research and Development Authority, a division of the U.S. Department of Health and Human Services, which will provide $40 million for the initial 18-month agreement, London-based Glaxo said in a statement today. If the accord is renewed over five years, the department will provide as much as $200 million, the drugmaker said.