If you have sneakers, wine bottles, and gloves crowding your desk, then you may already be aware of the findings from Yale Medical School: clutter can be painful to get rid of. Literally.
In the study, researchers asked groups of both self-described hoarders (who answered a call for people with "clutter problems") and non-hoarders to sort through junk mail, old newspapers, and other items they typically get thrown away. Then they asked what to hold onto and what to toss, with their brain activity tracked throughout.
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