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Before Nathalie Miller decided to walk away from Instacart, the grocery delivery start-up now worth more than $2 billion, she made a spreadsheet to analyze how much money she was leaving on the table.

She had been Instacart’s 20th employee, managing operations during a period of extremely rapid growth, and the sum could have been huge. She quit anyway. Like many strivers in Silicon Valley, she had a bigger plan: to start her own company that could not only make millions, but also fulfill a mission she believed in.

Image: Nathalie Miller in November at a co-working space in San Francisco. She was eight months pregnant and seeking investors. Credit Jason Henry for The New York Times