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BLACKBURG — Virginia Tech is talking to large pharmaceutical firms about cooperating with the university on research projects and opening offices inside Roanoke’s new health care innovation district. Michael Friedlander, founder of Virginia Tech Carilion Research Institute and a driving force behind the city’s growing health care industry, said that sort of partnership is only a concept, but affirmed that conversations are underway. City Manager Chris Morrill said Roanoke currently doesn’t have a major pharmaceutical company. Landing one would be the kind of payoff that city and university officials promised when they unveiled grand plans for a new health care hub in March.