Suppressing a newly discovered gene, drr-2, lengthens the lifespan of roundworms without reducing caloric intake, University of Michigan scientists have found.
Scientists who study aging have long known that significantly restricting food intake makes animals live longer, due to less oxidative damage in animal cells and a slower decline in DNA repair, a decline that normally occurs with age. It’s thought that limiting oxidative damage and slowing the decline in DNA repair could help postpone or avoid many age-related diseases.
Peach-fuzzed entrepreneurs like Mark Zuckerberg, 19 when he founded Facebook, and Larry Page and Sergey Brin, both 23 when they developed Google, have created a collective image of the successful innovator as youthful, brash, and brilliant. In turn, we’ve been taught that with middle age come calcified habits, outdated skills, and an aversion to risk. Sounds bad, right? Hey, it gets even worse when you consider that, by 2030, the average age will rise from 37 to 39 in the United States, from 40 to 45 in the European Union, and from 45 to 49 in Japan. The implication is that such figures, plus the post–baby boomer decline in birthrates, could leave swaths of the world with a deficit in creative potential. The question then becomes whether these places can continue to compete, grow, and create wealth with an aging pool of prospective entrepreneurs and workers. According to several new studies, the surprising answer is yes.