1. Venture capitalists are human. They like to invest in people they know…or in people their friends know. Thus, if you have no relationship with them, you are a mere business plan from a stranger. Work your network! You can get an audience with a referral, but it's really a long shot to go in cold.
2. Expect rejection. Most people I know had to speak with a dozen VCs before they got any traction -- and many had to do more than that. You are not going to fit with everyone. So, if you have a biotech start-up, find out who the people are who like your space.
3. Net it out. A long, boring Powerpoint presentation doesn't get anyone excited these days. That goes for VCs, too. The best presentations start with a slide that says, "Here are the eight things that I want you to walk away with." Everything else is "appendix."
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