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Liver colors: Diagnostics for All’s paper test indicates liver damage by changing color when a drop of blood is added. Normal enzyme concentrations turn the dots on the top row blue and yellow. Higher enzyme concentrations, indicators of liver damage, turn the color of the two dots pink, to match the “control” dots in the middle row. Credit: Diagnostics for All Diagnostics for All, a nonprofit startup in Cambridge, MA, has designed a cheap, disposable blood test for liver damage. The device uses a stack of paper the size of a postage stamp for a test of toxicity for drugs to treat HIV and tuberculosis.

Some antiretroviral therapies and many TB drugs are toxic to the liver. Patients on HIV and TB medication in rich countries are typically monitored every month for liver damage and taken off the treatment if liver damage becomes imminent. "In the U.S., [testing] is routine. It's expected, it's standard," says Nira Pollock, a faculty member at Harvard Medical School and infectious diseases expert at Beth Israel Deaconess Medical Center in Boston.

To read the full, original article click on this link: Technology Review: A Paper Test for Liver Damage

Author: Nidhi Subbaraman