Before Amazon, people purchased almost everything in person at a brick-and-mortar store. And while consumers still like to go shopping offline, 76 percent of adults in the U.S. now also consistently make online purchases, according to a recent poll conducted by Marist College and NPR. As Amazon’s customers discovered the undeniable convenience and ease of purchasing books online, it disrupted the entire retail experience. 

The last 10 years have seen a rev o lu tion in drug de vel op ment. Time lines have short ened, par tic u lar ly in on col o gy. Reg u la tors have opened up. In vest ment has sky rock et ed. Chi na be came a play er. Biotechs have mul ti plied as gene and cell ther a py has ex plod ed — of fer ing ma jor new ad vances in the way dis eases are treat ed, and some times cured.

So where are we head ed from here? I jour neyed out to San Fran cis co in Sep tem ber to dis cuss the an swer to that ques tion at Al lo gene’s open house. If the last 10 years have been an eye-open er, what does the next decade hold in store?

Image: https://endpts.com

In 2014, I founded a startup in Utah. The team was fired up and ready to invest the time, money, and effort required. But one colleague was taking on more risk than the rest of us. Seven years after earning a law degree, he was mired in $200K of student debt. He was unable to buy a house and ended up teaching himself to program to find better-paying work.

Networking may be a widely spoken and practiced concept, but it yields results only if done right.

For most businesses, their success can be traced back to powerful networking channels established over a course of time. When networks are made, it fosters the exchange of ideas to maintain long-term relationships and mutual confidence. But it requires that each person understands the other and their line of work properly to be able to add value - either as a client or otherwise.

While the world's population is expected to continue growing for decades to come, many countries face serious demographic headwinds, with low birth and immigration rates leading to aging and shrinking populations.

Japan is facing a "demographic time bomb" as young people in that country forgo having children. The BBC recently highlighted attempts to slow Bulgaria's population decline — the fastest in the world — by improving educational and economic opportunities in the country, making it more attractive for younger workers to stay rather than immigrating elsewhere in the European Union or to other countries.

Thanks to a yearslong boom in the world of venture capital, keeping tabs on biotech means constantly reading that some so-called startup is suddenly worth more than $1 billion. But just who is putting the horns on all these unicorns?

Welcome back to “The Facts, STAT!”, a not-infrequent STAT video series in which our reporters briefly explain the need-to-know basics of issues in the world of health care and biotech.

Image: https://www.statnews.com - From Video

Armed with some data from our friends at CrunchBase, I broke down the largest US startup funding rounds from the third quarter of 2019. I have included some additional information such as industry, company description, round type, founders, and total equity funding raised to further the analysis. To maintain a focus on tech-enabled companies, real estate, biotech, and lending companies were excluded.  This report only contains equity fundings.

Image: https://www.alleywatch.com

As a historian, I know that Britain is at its greatest when we reach out to the world, when we break free of our island mentality, when we see ourselves yes, as a powerful, dynamic and proud nation, but also as an important part of a much greater whole.

And nowhere in our society is this clearer than in our universities and wider knowledge economy. After Brexit, we want not just a friendly relationship with our European neighbours and allies, but also to reach out and build better connections with the wider world.

Image: Chris Skidmore said at the universities he had visited he had seen research and innovation on an international scale. - https://www.yorkshirepost.co.uk

AsianScientist (Oct. 11, 2019) – Whether it is a fresh idea, a new product or a revamped process, innovation can take many forms and is a key fuel for growth in companies. Sustaining innovation, however, is an uphill task, akin to keeping a plane in flight even as its wings and wheels are being upgraded—a company may find it difficult to ideate and carry out research and development (R&D) when it is busy with day-to-day operations.

The wisest explorers make sure to take a look at a map before their journey. Or at the very least, have one handy.

When diving into a startup or tech ecosystem, it can be helpful to have a map, too, and that’s what we want this “Ecosystem at a Glance” document to serve as: a starting place, on-boarding tool and refresher for those new to and familiar with the city’s innovation economy. At the very least, it will help you sound like you know your stuff at your next meetup.

Image: american inno

Thank you BioHealth Innovation, Inc. and AstraZeneca for another successful hashtag#BioHealth Capital Region BioBowl last night. The Children's National Hospital team had a blast. And, we loved the slogan on our T-Shirts "Advancing Science. Accelerating Innovation."

Richard Bendis Judy Costello @Albine Martin, Ph.D. Luis Gutierrez Jeff Walpole Sara Alyamani Whitney Black, MHA Justin Opfermann Lisa Romano BioBuzz Gayatri Varma Jarrod Borkat TEDCO Arti Santhanam Anthony Ho

hashtag#innovate4kids hashtag#bhcr hashtag#jlabs hashtag#pediatrics hashtag#healthcareinnovation hashtag#innovators

Venture capitalists are pouring cash into U.S. biotechs at a rate set to replicate 2018’s record deal count, according to PitchBook and the National Venture Capital Association’s third-quarter Venture Monitor report.

In the first three quarters alone, VCs struck 609 biopharma deals — the majority of which were Series A or B — and contributed $11.5 billion in investments.

Yesterday, we had a chance to talk with longtime venture investor Brad Feld of Foundry Group, whose book “Venture Deals” was recently republished for the fourth time, and for good reason. It’s a storehouse of knowledge, from how venture funds really work to term sheet terms, from negotiation tactics to how to choose (and pay for) the right investment banker.

Image: Dani Padgett / StrictlyVC

Every entrepreneur and business leader believes that he or she has the full trust of their team and their customers, and in fact most do in the beginning. In my experience, most business professionals still believe in the old proverb, “trust but verify.” In this context, that means you trust your leaders initially, but you look for signals that your trust in them is deserved and reciprocated.

Image: https://blog.startupprofessionals.com

First, you must identify the sector in which you want to start your business. You should then do a proper market research to decide if this idea will bring you fruitful results or not. In addition, you will need to talk to a few friends who could help you achieve your goals.

Usually, people are afraid to start a business for fear of failure. But there is something else that can become an obstacle, it is the lack of money. Some people have enough money in their savings account to realize their dream of start-up. But many people do not have enough money to pursue their goals. Fortunately, there are many ways to finance your start-up.

With a deal-or-no-deal Brexit and a possible US-China trade truce, there is almost too much happening. Germany is in recession, a fate Britain just escaped – an economics columnist is spoilt for choice.

This weekend, though, I’m focusing on Amazon, big tech and the future of capitalism. One reason is that I spoke with a senior former Amazon executive. And what he had to say was important.

Who do you think makes more typos or mistakes, desktop or mobile typists? According to a recent infographic from Fenetic Wellbeing, desktop users are making 3X more errors than mobile users.

Even though the technology of what we type on has changed, the concept is pretty much the same since 1829. This was the year the first American patent was granted to William Austin Burt for what will eventually become the typewriter.

You might consider grammar an annoying technicality, a minuscule detail of speech and writing not worth much effort.

But a 2012 study from the Society for Human Resources and Management showed that 45% of employers planned to increase training for grammar and other language skills (meaning they were unhappy with the levels.)

Image: Robert Libetti/ Business Insider

For most of us, getting enough sleep isn't a life-or-death kind of thing. Sure, we might make poor decisions, but our being sleepy at the marketing meeting tomorrow is not going to get someone killed. 

During WWII, though, the US military quickly got hip to the fact that if fighter pilots didn't get sleep, their poor decisions had dire consequences. Their mishaps included errors that resulted in their being shot down — or shooting down guys on their own side.

Very cool seeing so many people from the different BioHealth Capital Region. 30+ lanes of companies. BioHealth Innovation, Inc. BioBuzz