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Unhappy water: Chemical modeling software called WaterMap can predict how water molecules, shown here in red and green, can influence how strongly drug candidates bind to their intended target.  Credit: Schrödinger

Most pharmaceutical companies use software to model chemical interactions, with the hope of speeding up the drug development process.  But it's typically a small component of a complex array of approaches. Nimbus Discovery, a startup based in Cambridge, Massachusetts, is using computational chemistry to drive the entire process.

The company emerged from a partnership with Schrödinger, a maker of computational drug discovery software, and venture capital firm Atlas Venture. Nimbus will use Schrödinger's software, computing power, and modeling experts to develop drugs for disease-linked proteins that have historically been difficult to target.

 

To read the full, original article click on this link: Driving Drug Discovery with Computational Chemistry - Technology Review

Author: EMILY SINGER