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"Shark Tank" investor Lori Greiner started with a single invention, an earring holder, in 1997 and grew it into a multimillion-dollar family of businesses with products on QVC and in the world's biggest retailers.

On her path to more than 400 inventions and 120 patents, she tells Business Insider that she constantly reminded herself of the advice that both her father and her husband gave: "Don't let business get personal. It's just business. Shrug it off."

Image: Diane Bondareff/Invision for Staples/AP