The latest surge in Covid-19 cases generated by the Delta variant is throwing a wrench into plans to have employees return to the office. How can leaders deal with the uncertainty? This article offers six principles: 1) Continue to prioritize employees’ well-being; 2) Be adaptive; 3) Massively step up your communications; 4) Rethink your biases about work; 5) Learn from Zoom natives; and 6) Don’t rush to declare the future.