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This illustration provided by the Centers for Disease Control and Prevention in January 2020 shows the 2019 Novel Coronavirus (2019-nCoV). This virus was identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China. (CDC via AP)

As the United States approaches the second anniversary of its initial COVID-19 shutdowns, we're daring to dream about what the end of the pandemic might look like. With omicron cases plummeting, indoor mask mandates in every state but Hawaii are set to expire—a change that would have seemed unthinkable just weeks ago.