Every business founder knows the need for a culture that promotes continuous innovation, an entrepreneurial spirit, and one that creates sustainable value across all functions in the business. Yet most don’t really know how to create that environment, or assess when they have achieved it. They only know in retrospect too late when they don’t have it, and the business is in crisis mode.

Image: https://blog.startupprofessionals.com

What’s going down in Silicon Valley? The headlines tell a big part of part of the story, but only one part. How complete and accurate a picture one gets about the social justice uprisings, and the ‘Big Tech’ rumblings out there, depends upon how far one is from Highway 101.

The tortured soul searching and social earth-scorching now unleashed in the domain of Big Tech is quite a departure from the quiet decorum that resides up on Sand Hill Road, just above the Stanford University campus. The air these days is full of nasty reprisals and social revenge, the kind that occur spontaneously in all post war conflicts.

Image: http://www.thenextsiliconvalley.com

In her book, Being Wrong: Adventures in the Margin of Error, author Kathryn Schulz writes, “Our love of being right is best understood as our fear of being wrong.” In other words, our commitment to believing that we know exactly what’s happening and why, and what to do about it, is reinforced by us trying very, very hard not to think about this possibility: “What if I’m making a mistake?” Or perhaps, even worse, “What if I already made one?”

What’s the one thing on your plate that you’ve been putting off making a decision on? Whether it’s a simple decision such as choosing which duct-cleaning company to hire or a more complex one such as whether to accept a new job offer, sitting on a decision can make you feel like you’re paralyzed. You tell yourself, “that’s enough, just pick one and move on.” But the second you make a choice, thoughts of “am I doing the right thing?” start to flood in.

The US Patent and Trademark Office (USPTO) and Department of Commerce have “restored American leadership in the protection of intellectual property”, according to USPTO director, Andrei Iancu. The US was ranked number one as the overall global leader on the US Chamber of Commerce Global Innovation Policy Center (GIPC)’s International IP Index, released on 6 February, which ranks the IP climate in 50 world economies.

The US was ranked in second place for patents, related rights, and limitations.

Image: http://www.ippromagazine.com

The life sciences industry is taking off, with the medical technology and biotech sectors expected to grow further as traditional pharmaceutical companies are joined by startups and incubator labs driving new research and development. And with life sciences innovation rising, so is demand for the space in which to innovate.

To keep pace with the evolving ecosystem for precision medicine, pharma players must be attuned to three crucial components: data collection, individualized solutions, and supporting business models.

As originally conceived, personalized medicine referred to the tailoring of medical treatment to the individual characteristics of each patient,1 ultimately leading to a shift in the clinical treatment paradigm from a trial-and-error approach to “the right drug, for the right patient, at the right time.” Today, a combination of public investment, biotechnology development, and digitization of health profiles has evolved personalization beyond therapy selection and into the realm of drug discovery, how care is planned for and delivered, and increasingly, to how we as consumers engage with companies seeking to improve health (exhibit). Driving this transformation are advances in diagnostics, digital devices, and imaging, alongside an arsenal of analytics tools working across a multitude of institutions and stakeholders.

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Whether you’re dealing with the common cold, the flu or a stomach bug, you’ve probably noticed that your symptoms feel worse at night.

You’re not imagining things. Research suggests that your body’s circadian rhythms—as well as some other factors—can exacerbate your symptoms after sundown.

Along with regulating your sleep, your body’s circadian clocks help manage your immune system, says Michael Smolensky, a biological rhythm researcher and adjunct professor of biomedical engineering at the University of Texas.

POTOMAC, Md., Feb. 5, 2019 — PitchMasters™, a workshop-style event for entrepreneurs preparing for their first institutional capital raise, held its 2019 Kick Off and Alumni Event on Jan. 30, 2019. Four emerging startup companies, Skipiit, Trove Therapeutics, Uplift and VERALOX Therapeutics, practiced their pitching skills and gained insights from experienced entrepreneurs, investors, industry influencers and fellow PitchMasters™ alumni.

If you were asked to pick the car that was the most technically influential on the greatest number of modern cars, what would you pick? Would you go as far back as the Ford Model T, the real, widely accessible proof of concept of the automobile? An early Panhard, which defined the Systeme Panhard, the front-engine, rear-drive layout that defined cars for so long? Maybe you’d be clever and pick the BMC Mini, which, with its transverse front engine, front-wheel drive layout set the template for the vast majority of modern cars? One car I think most people wouldn’t pick, though, would be the Autobianchi Primula, and I think that’s a big mistake.

Image: https://jalopnik.com

Foxconn was supposed to bring 13,000 jobs to Wisconsin. It was supposed to revitalize American manufacturing. It was supposed to, as President Trump put it, be “one of the great deals ever.” Most of all, it was meant to be a living proof of concept that manufacturing could come back to the U.S. and that Trump was the man to do it.

Instead, the much-discussed project is a multibillion-dollar boondoggle that is hurting the very people it was meant to help.

Looks like we’ll see more cryptocurrency in crowdfunding

In less than a decade, crowdfunding has already been recognised as one of the most typical methods of fundraising for technological products.

It has assisted millions of innovators to bring their ideas into the market.

Given the exponential growth of cryptocurrencies within the last few years, crowdfunding has attained new milestones and an increasingly promising prospect despite the slowdown of Initial Coin Offerings (ICO).

Utilization of digital health services and technologies has been on the rise since we first began surveying the US adult population in 2015. Budding choices of wearables, apps, telemedicine, and other tech-enabled services make it easy for consumers to test out what it might be like to “go digital” for their health. In the first three years, our annual survey showed that tools for fitness and wellness represented a common (and low-risk) entry point for consumers to experiment with products that fit neatly into their already tech-enabled lifestyles. In the 2018 data that we examined for this report, we saw something different. Consumers continue to go digital and are now doing so not just out of curiosity or for general fitness and well-being—but with the intention to address concrete health needs.

Image: https://rockhealth.com

Mayo Clinic and scientific research company Leidos are teaming up on a new effort surrounding patient-focused innovation.

Together, the two organizations will create an accelerator on Mayo Clinic’s Jacksonville, Florida campus. More specifically, it will be within Mayo’s Life Sciences Incubator campus, which is a Jacksonville medtech hub that advances products from the research lab and into the clinic.

SAN FRANCISCO — Technology start-ups worth $1 billion, once as rare as unicorns, are now plentiful enough and old enough that there’s a new generation behind them — one that looks very different.

Silicon Valley’s current crop of highly valued tech start-ups, which include now-household names like Uber and Airbnb, all benefited from the spread of smartphones and cheap cloud computing. Many of these companies built global empires by simply taking existing businesses — like taxis, food delivery and hotels — and making them mobile. Some of the start-ups became giants: Uber, for instance, may reach a $120 billion valuation this year.

I often recommend business networking as the most effective way for a startup founder to find investors, advisors, and even key executive candidates. But what if you are an introvert, or new to this game, and don’t know where or how to start?

The answer is still the same, but I have learned over the years that there is an etiquette to this process, just like there is for social networking.

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A recent research study found that 48% of business-to-business salespeople are afraid of making cold calls. Sadly, salespeople who are afraid of making cold calls have trouble hitting their quotas, are more stressed, and are likely making less money than their counterparts who don’t share this phobia.

A Fortune 100 automotive company is exploring a new technology on the periphery of their core business. The executives in charge believe they have struck on a possible breakthrough, but as they push the project into uncertain terrain, their traditional signposts for decision-making are no longer relevant in this new context. They need a new method for coming to strategic decisions within this unfamiliar and turbulent environment, but how?